For adjunctive use in adults age 22+ on ADT1
Tap into the brain’s power to take on MDD symptoms1
Rejoyn may strengthen connections in the brain by harnessing neuroplasticity.1-3
Rejoyn is a prescription app that uses brain training exercises to help enhance cognitive control of emotion.1
ADT=antidepressant therapy; MDD=major depressive disorder.
Meet Rejoyn
Rejoyn, when used alongside ADT, can treat MDD symptoms differently.1,4

Rejoyn is designed to improve emotion regulation and processing
through 2 core components1:
Cognitive behavioral therapy (CBT)-based video lessons

Cognitive-emotional training (CET) exercises
Clinically demonstrated efficacy and safety1
The Mirai clinical trial evaluated the effectiveness and safety of Rejoyn as an adjunct to ADT in patients with MDD, compared with a cognitive-training control, or Sham. Patients treated with Rejoyn experienced1:
- Reduced MDD symptoms1
- Zero adverse events related to Rejoyn1
Including detailed safety information.
High adherence and satisfaction rates1
- 88.1% of patients using Rejoyn adhered to treatment in
the clinical trial, defined as completing at least 12
of the 18 treatment sessions.1 - 76%of patients using Rejoyn reported that they were “extremely satisfied” (37.1%) or “satisfied” (38.9%) with the experience.1
End-to-end nurse support
Patients can call the nurse support line at 1-833-Y-REJOYN (1-833-973-5696) for assistance throughout their 6-week treatment with Rejoyn. Available Monday through Friday, 8 AM to 8 PM ET, excluding holidays.
Provide patient-powered adjunctive treatment for MDD symptoms
Provide patient-powered adjunctive treatment for MDD symptoms
With Rejoyn, patients can access treatment on their smartphones, on their own time. New exercises are unlocked at midnight the day they become available and expire at the end of each week.
Completing the CET brain exercises in Rejoyn takes about 20 to 30 minutes each, and the CBT-based video lessons take about 5 minutes each, so patients can fit treatment into their own schedules.

An app, prescribed like a pill1
Learn how to provide Rejoyn to the patients in your practice.
Frequently asked questions
Unlike wellness apps, the Rejoyn app is in a class of software-based treatments called prescription digital therapeutics (PDTs). Rejoyn is regulated by the FDA and requires a prescription from a healthcare professional.4
There are 2 ways to prescribe Rejoyn: e-prescribe or refer for a virtual consult. If you are a licensed prescriber, you can prescribe Rejoyn through your electronic health record system. If you are a behavioral health clinician, you can direct your patients to the Rejoyn patient website. There they can follow a link to schedule a virtual consult from Wheel, a telehealth provider, for a $29 fee.
Whether you e-prescribe or refer for a virtual consult, a patient's prescription will be sent directly to CaryRx pharmacy—this is the online pharmacy that dispenses access codes for Rejoyn.
Licensed prescribers can learn how to find CaryRx pharmacy in the electronic medical record here.
CaryRx pharmacy is an online pharmacy that specializes in digital products and dispenses Rejoyn. You can call 1-833-Y-REJOYN (1-833-973-5696) Monday through Friday, 8 AM to 8 PM ET, excluding holidays, and select from a list of menu options that will connect you to CaryRx pharmacy.
A patient's prescription will be sent directly to CaryRx pharmacy for processing, payment, and fulfillment.
- CaryRx pharmacy will follow up with your patient to collect payment using their credit or debit card. Please note that insurance providers may not cover prescription digital therapeutics. As a medical device, Rejoyn is reimbursable by HSA/FSA
- Once payment has been received, the pharmacy will provide your patient with an 8-digit access code for Rejoyn and will also text and email it within a couple of minutes
- Your patient can download the Rejoyn app, set up their profile, and enter their access code to unlock treatment
FSA=flexible spending account; HSA=health savings account.